| Genetic Modification |
| Genome Editing, Transgenic & Virus Core | Jen Orwig |
| Magee-Womens Research Institute’s Genome Editing, Transgenic, and Virus (GETV) Core Facility provides leadership, technical expertise, advice and training for investigators both within and outside the University of Pittsburgh community. Services are available in the areas of molecular cloning (plasmid, virus, CRISPR/Cas9), viral vectors (lentivirus, adenovirus, adeno-associated virus), and animal services (transgenic, knockout, cryopreservation, re-derivation, and more). Location: Oakland, MWRI |
| Innovative Technologies Development Core | Sebastien Gingras |
| The Innovative Technologies Development Core provides expert design and implementation of gene targeting strategies using various methods, including CRISPR-Cas9, in mice and cells. Location: Shadyside, FORD |
| Mouse Embryo Services Core | Chunming Bi |
| The Mouse Embryo Services Core offers a full range of services of genetically modified mouse lines including sperm/embryo cryopreservation and rederivation as well as consultation on mouse colony maintenance and breeding. Location: Shadyside, FORD |
| Husbandry Support |
| Animal Facility, HCC | Megan Lambert |
| Animal husbandry and research support located at the Hillman Cancer Center. Shadyside, HCC |
| Drosophila Facility | Michael Palladino |
| The Drosophila Facility specializes in producing Drosophila media and making it available to local investigators. The media is provided in trays of vials (standard wide) or bottles Location: Oakland, BST3 |
| Gnotobiotic Animal Core Laboratory | General email |
| The Gnotobiotic Animal Core Laboratory is a BSL2-compliant mouse facility providing isolators for studies requiring a controlled microbiotic environment. All husbandry and upkeep services are provided. Additional specialized support is also available.
Location: Oakland, BST3 |
| Mouse Embryo Services Core | Chunming Bi |
| The Mouse Embryo Services Core offers a full range of services of genetically modified mouse lines including sperm/embryo cryopreservation and rederivation as well as consultation on mouse colony maintenance and breeding. Location: Shadyside, FORD |
| Model Organism Imaging |
| Advanced Imaging Center | T. Kevin Hitchens |
| The Advanced Imaging Center at Pitt is a high-field magnetic resonance imaging (MRI) and spectroscopy (MRS) facility allowing high-resolution in vivo rodent imaging and ex vivo imaging of specimens and tissue samples for applications in life science, biomedical and preclinical imaging research. Location: Southside, MGOWN |
| Animal Imaging Core Laboratory at the John G. Rangos Sr. Research Center | Yijen Wu |
| The Animal Imaging Core Laboratory at the John G. Rangos Sr. Research Center provides in vivo and ex vivo multimodal imaging services (MRI, MRS, ultrasound, CT, PET, SPECT, and IVIS) and microinjection for all areas of preclinical anatomical imaging, functional imaging, and molecular imaging, from small rodents, rabbits, goats and pigs to nonhuman primates as well as non-biological samples. Location: Lawrenceville, RANCH |
| Pre-clinical In Vivo Imaging Facility, Hillman Cancer Center | Jessie Nedrow |
| The Preclinical In Vivo Imaging Facility at UPMC Hillman Cancer Center offers MR, PET-CT, optical and ultrasound for small animals. Location: Shadyside, HCC |
| Small Animal Ultrasonography Core | Anja Popey |
| The Small Animal Ultrasonogrphy Core provides high frequency ultrasound for non-invasive, in vivo, real-time, high-resolution imaging of tissue structure and function in small animals.
Location: Oakland, BST |
| Pathogen Control |
| Gnotobiotic Animal Core Laboratory | General email |
| The Gnotobiotic Animal Core Laboratory is a BSL2-compliant mouse facility providing isolators for studies requiring a controlled microbiotic environment. All husbandry and upkeep services are provided. Additional specialized support is also available.
Location: Oakland, BST3 |
| Regional Biocontainment Laboratory | Paul Duprex |
| The Regional Biocontainment Laboratory maintains BSL2+ and BSL3 compliant laboratory space for use by investigators working with controlled pathogens. Investigator personnel must receive training and perform all laboratory operations. The facility does not provide labor support. Location: Oakland, BST3 |
| Preclinical Studies |
| Advanced Imaging Center | T. Kevin Hitchens |
| The Advanced Imaging Center at Pitt is a high-field magnetic resonance imaging (MRI) and spectroscopy (MRS) facility allowing high-resolution in vivo rodent imaging and ex vivo imaging of specimens and tissue samples for applications in life science, biomedical and preclinical imaging research. Location: Southside, MGOWN |
| Center for Preclinical Studies | Shawn Bengston |
| The Center for Preclinical Studies is a full-service in-vivo large animal model testing facility supporting both exploratory and later stage preclinical testing for complex medical devices and novel therapies. Industry-initiated surgeon qualification training for human clinical trials can be supported on-site. Rigorous quality assurance and data archiving programs provide a high degree of data integrity and complete study reconstruction. Location: Southside, MCGOWN |
| Pittsburgh Pepper Center | General email: |
| The Pepper Research Network on Aging (PRNA) maintains two registries that are available for Pepper-approved researchers who are conducting aging-related research at the University of Pittsburgh. These registries include the Community Registry and the Platinum Senior-Living Registry. Location: Oakland, KAU |
| Preclinical Phenotyping Core | General email |
| The Preclinical Phenotyping Core provides access to and expert professional assistance in characterization of behavioral and physiological phenotypes in rodent models. Location: Oakland, BST3 |
