| Genomics |
| Cancer Bioinformatics Services, UPMC Hillman Cancer Center | Riyue Bao or Uma Chandran |
| The Cancer Bioinformatics Services at UPMC Hillman Cancer Center provides bioinformatics support for translational genomics using sequencing, arrays, single cell, and other technologies. Location: Shadyside, HCC and Oakland, MURDC |
| Genomics Analysis Core | Uma Chandran |
| The Genomics Analysis Core focuses on bioinformatics analysis of genomic data with emphasis on rigor and reproducibility. Professional analytical staff support all aspects of translational studies - from experimental design to data analysis to publication. Location: Oakland, MURDC |
| Health Sciences Sequencing Core at Children's Hospital of Pittsburgh | Dr. Will MacDonald |
| The Health Sciences Sequencing Core (HSSC) at UPMC Children's Hospital of Pittsburgh offers full-service next generation sequencing; including RNA/DNA extraction, library generation and sequencing on Illumina NextSeq2000 or MiSeq sequencers. Protocols are established to accept a wide range of input quantity and quality. The HSSC also specializes in spatial transcriptomics and offers full-service options for 10x Genomics Visium HD and Xenium. Location: Lawrenceville, RANCH |
| High Throughput Genome Center | Jianhua Luo, MD |
| The High Throughput Genome Center supports high throughput paralleled sequencing for genome, transcriptome and epigenome analyses through Illumina and Oxford nanopore platforms, and array through Affymetrix platform. In addition, the center provides collaboration on single-cell transcriptome and multi-omic sequencing. For spatial biology, we provide Cytassist and Stereo-Seq platforms for transcriptome analysis. The center also provides extensive bioinformatic analyses to investigators through collaboration. Location: Oakland, SCAIF |
| Single Cell Core | Heidi Monroe |
| The Single Cell Core provides library preparation and analysis using the 10X Genomics Chromium platform. All 10X Genomics single cell applications are fully supported including gene expression, V(D)J B cell and T cell immune profiling, ATAC, Multiome (gene expression with ATAC), cell surface protein markers and FLEX (single cell processing of FFPE tissue sections and formaldehyde fixed cells and tissues). Location: Oakland, BSTWR-S |
| Metabolomics |
| Cancer Bioinformatics Services, UPMC Hillman Cancer Center | Riyue Bao or Uma Chandran |
| The Cancer Bioinformatics Services at UPMC Hillman Cancer Center provides bioinformatics support for translational genomics using sequencing, arrays, single cell, and other technologies. Location: Shadyside, HCC and Oakland, MURDC |
| Genomics Analysis Core | Uma Chandran |
| The Genomics Analysis Core focuses on bioinformatics analysis of genomic data with emphasis on rigor and reproducibility. Professional analytical staff support all aspects of translational studies - from experimental design to data analysis to publication. Location: Oakland, MURDC |
| Health Sciences Mass Spectrometry Core | General email |
| The Health Sciences Mass Spectrometry Core provides liquid chromatography high resolution mass spectrometry (LC-HRMS) services for metabolomics, lipidomics and proteomics. We also provide proteomics analysis using the O-link Midplex and Reveal platforms. Expert staff provide assistance throughout the full lifespan of all projects from experimental design and sample preparation through statistical analysis and interpretation of datasets. Location: Oakland, BST3 |
| OMICS Data Analysis |
| Bioinformatics Core Facility at the John G Rangos Sr. Research Center | Dhivyaa Rajasundaram |
| The Bioinformatics Core Facility at the John G. Rangos Sr. Research Center provides bioinformatics as well as biostatistics services across a wide range of disease domains. The next-generation sequencing data analysis includes, but is not limited to, whole genome-, whole exome-, bulk and single cell epigenome-, bulk and single cell transcriptome, spatial transcriptome, microbiome, metabolome, proteome and lipidome data analysis. The facility specializes in T-, and B- cell repertoire data analysis, multi-omics initiatives, and multimodal analysis. Shiny dashboard and other web application development is also supported. Location: Lawrenceville, RANCH |
| Cancer Bioinformatics Services, UPMC Hillman Cancer Center | Riyue Bao or Uma Chandran |
| The Cancer Bioinformatics Services at UPMC Hillman Cancer Center provides bioinformatics support for translational genomics using sequencing, arrays, single cell, and other technologies. Location: Shadyside, HCC and Oakland, MURDC |
| Genomics Analysis Core | Uma Chandran |
| The Genomics Analysis Core focuses on bioinformatics analysis of genomic data with emphasis on rigor and reproducibility. Professional analytical staff support all aspects of translational studies - from experimental design to data analysis to publication. Location: Oakland, MURDC |
| Health Sciences Mass Spectrometry Core | General email |
| The Health Sciences Mass Spectrometry Core provides liquid chromatography high resolution mass spectrometry (LC-HRMS) services for metabolomics, lipidomics and proteomics. We also provide proteomics analysis using the O-link Midplex and Reveal platforms. Expert staff provide assistance throughout the full lifespan of all projects from experimental design and sample preparation through statistical analysis and interpretation of datasets. Location: Oakland, BST3 |
| High Throughput Genome Center | Jianhua Luo, MD |
| The High Throughput Genome Center supports high throughput paralleled sequencing for genome, transcriptome and epigenome analyses through Illumina and Oxford nanopore platforms, and array through Affymetrix platform. In addition, the center provides collaboration on single-cell transcriptome and multi-omic sequencing. For spatial biology, we provide Cytassist and Stereo-Seq platforms for transcriptome analysis. The center also provides extensive bioinformatic analyses to investigators through collaboration. Location: Oakland, SCAIF |
| Single Cell Core | Heidi Monroe |
| The Single Cell Core provides library preparation and analysis using the 10X Genomics Chromium platform. All 10X Genomics single cell applications are fully supported including gene expression, V(D)J B cell and T cell immune profiling, ATAC, Multiome (gene expression with ATAC), cell surface protein markers and FLEX (single cell processing of FFPE tissue sections and formaldehyde fixed cells and tissues). Location: Oakland, BSTWR-S |
| Proteomics |
| Cancer Bioinformatics Services, UPMC Hillman Cancer Center | Riyue Bao or Uma Chandran |
| The Cancer Bioinformatics Services at UPMC Hillman Cancer Center provides bioinformatics support for translational genomics using sequencing, arrays, single cell, and other technologies. Location: Shadyside, HCC and Oakland, MURDC |
| Genomics Analysis Core | Uma Chandran |
| The Genomics Analysis Core focuses on bioinformatics analysis of genomic data with emphasis on rigor and reproducibility. Professional analytical staff support all aspects of translational studies - from experimental design to data analysis to publication. Location: Oakland, MURDC |
| Health Sciences Mass Spectrometry Core | General email |
| The Health Sciences Mass Spectrometry Core provides liquid chromatography high resolution mass spectrometry (LC-HRMS) services for metabolomics, lipidomics and proteomics. We also provide proteomics analysis using the O-link Midplex and Reveal platforms. Expert staff provide assistance throughout the full lifespan of all projects from experimental design and sample preparation through statistical analysis and interpretation of datasets. Location: Oakland, BST3 |
| Spatial Biology |
| Cancer Bioinformatics Services, UPMC Hillman Cancer Center | Riyue Bao or Uma Chandran |
| The Cancer Bioinformatics Services at UPMC Hillman Cancer Center provides bioinformatics support for translational genomics using sequencing, arrays, single cell, and other technologies. Location: Shadyside, HCC and Oakland, MURDC |
| Genomics Analysis Core | Uma Chandran |
| The Genomics Analysis Core focuses on bioinformatics analysis of genomic data with emphasis on rigor and reproducibility. Professional analytical staff support all aspects of translational studies - from experimental design to data analysis to publication. Location: Oakland, MURDC |
| Health Sciences Sequencing Core at Children's Hospital of Pittsburgh | Dr. Will MacDonald |
| The Health Sciences Sequencing Core (HSSC) at UPMC Children's Hospital of Pittsburgh offers full-service next generation sequencing; including RNA/DNA extraction, library generation and sequencing on Illumina NextSeq2000 or MiSeq sequencers. Protocols are established to accept a wide range of input quantity and quality. The HSSC also specializes in spatial transcriptomics and offers full-service options for 10x Genomics Visium HD and Xenium. Location: Lawrenceville, RANCH |
| High Throughput Genome Center | Jianhua Luo, MD |
| The High Throughput Genome Center supports high throughput paralleled sequencing for genome, transcriptome and epigenome analyses through Illumina and Oxford nanopore platforms, and array through Affymetrix platform. In addition, the center provides collaboration on single-cell transcriptome and multi-omic sequencing. For spatial biology, we provide Cytassist and Stereo-Seq platforms for transcriptome analysis. The center also provides extensive bioinformatic analyses to investigators through collaboration. Location: Oakland, SCAIF |