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Searches can use "boolean" logic:

Prefixing a search term with a "+" denotes boolean "AND" operator.
Prefixing a search term with a "-" denotes boolean "AND NOT" operator.
Absence of a prefix is interpreted as "OR" operator.

Examples: ("Search term" => Logical interpretation)
"computing DNA" => "computing" OR "DNA"
"+computing +DNA" => "computing" AND "DNA"
"+computing -DNA" => "computing" AND NOT "DNA"

Wildcard "*" searches are also valid, but only at the end of a word.

"*" is interpreted as one or more characters.

Example:
"comput* +DNA" => "comput*" AND "DNA"

Phrases can be enclosed in double-quotes (")

Example:
""mass spec*" +proteomics" => "mass spec*" AND "proteomics"

All searches are case-insensitive.
Citations are an essential shared resource support. Acknowledge facilities as requested in papers, posters, and talks.
Other Laboratory Support Other Laboratory Support
Specialized Assays
Biobehavioral Oncology FacilityFrank Jenkins
The Biobehavioral Oncology Facility at UPMC Hillman Cancer Center provides wet lab support for specimen processing and a wide range of assays for biobehavioral researchers lacking access to wet lab space and/or necessary expertise. Location: Shadyside, HCC
Biomolecular NMR Shared ResourceAndrew Hinck
The Biomolecuar NMR Shared Resource (bioNMR-SR) is to provide to University of Pittsburgh School of Medicine faculty with state-of-the-art resources for detailed molecular analysis, including full structure determination of biological macromolecules with essential functions in normal cells and disease. The bioNMR-SR is equipped for analysis of biomolecules in both solution and in the solid state, with four solution-based NMR spectrometers (all equipped with high sensitivity cryogenically-cooled probes) and two solid state-based NMR spectrometers. Together, these provide a complementary set of tools for detailed molecular analysis of the structure, dynamics, and interactions of biological macromolecules. Location: Oakland, BST3
Cancer Pharmacokinetics and Pharmacodynamics Facility, UPMC Hillman Cancer CenterRobert Parise, PhD
The UPMC Hillman Cancer Center Cancer Pharmacokinetics and Pharmacodynamics Facility provides accessible, economical, comprehensive, and state-of-the-art bioanalytical, pharmacokinetic and pharmacology research services that support preclinical and clinical research programs focused on oncology at UPMC Hillman Cancer Center and medical institutions nationwide. Resources include HPLC-UV/fluorescence, ICP-MS, LC-MS/MS, LSC, ELISA, and in vivo rodent procedures, as well as advanced PK software suites and expertise for preclinical and clinical projects. Location: Shadyside, HCC
CRISMA Clinical Research Biospecimen CoreKelly Urbanek or Ali Smith-Scott
CRISMA Clinical Research Biospecimen Core: The CRISMA Clinical Research and Biospecimen Core Laboratory (CRBC Lab) offers a range of biomarker/analyte quantification services utilizing various platforms – Luminex, ELLA, and ELISA. In addition, the lab can isolate and quantify DNA from whole blood samples. The CRBC Lab technicians have extensive experience supporting multiple projects from multicenter NIH-funded clinical trials to pilot studies. Location: Oakland, SCAIF
Luminex Core Laboratory, UPMC Hillman Cancer CenterDenise Prosser
The Luminex Core Laboratory at UPMC Hillman Cancer Center performs assays using multiplexed, bead-based immunochemistry on minimal sample volumes. Luminex technology provides a method for profiling of up to 100 different proteins, peptides, or DNA molecules in a single microtiter well. Results have strong concordance to ELISA and mass spectrometry. Thousands of commercially validated kits are available for purchase through the core laboratory. A list of these assays can be requested. Location: Shadyside, HCC
Small Molecule Biomarker CoreRaymond West
The Small Biomarker Core provides accurate and sensitive quantitative analysis in biological samples, with or without sample processing, using state-of-the-art ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). In addition to well qualified assays for common targets, experienced, knowledgeable personnel can provide assay development for novel targets Location: Oakland, SALKP
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